Aesthetic Program
Biostimulation
Biostimulation is an injection treatment that stimulates the process of collagen, elastin and new skin cell production directly in the skin layer.
It does not only make the skin look plump temporarily like fillers or skin boosters, but helps the skin become fuller, firmer and tighter in a long-lasting way from within.
It does not only make the skin look plump temporarily like fillers or skin boosters, but helps the skin become fuller, firmer and tighter in a long-lasting way from within.
Benefits of Biostimulation
- Rejuvenates the skin from inside out, not just by adding artificial substances
- Results look natural and gradually improve as the body produces more collagen
- Stimulates the body to produce its own collagen and elastin
- Does not change the face shape, not swollen, not overdone
Biostimulation Substance Groups
Examples of key substance groups used in Biostimulation programs to stimulate collagen production and restore the skin from within.
| Group | Main Substance | Example Products |
|---|---|---|
| PLLA | Poly-L-Lactic Acid | Sculptra, AestheFill, Lenisna |
| PCL | Polycaprolactone | Gouri |
| PN / PDRN | Salmon DNA | Rejuran, Plinest, Nabota Sprak (PN) |
Biostimulation Brands Available in Thailand
There are now many Biostimulation brands to choose from. Each brand has different main active ingredients, mechanisms of action, key benefits and duration of results.
The doctor will evaluate and select what is suitable for each person’s skin condition and needs.
| Brand | Main Active Ingredient | Country of Origin | Mechanism of Action | Key Benefit | Duration |
|---|---|---|---|---|---|
| Sculptra | PLLA | United States | Stimulates long-term collagen production | Lifts and tightens the whole face with natural fullness | Around 1–2 years |
| AestheFill | PLLA | South Korea | Works similarly to Sculptra but is easier to dissolve and adjust | Firm face, tight skin, lifted mouth corners | about 1 year |
| Juvelook | HA + PLLA | South Korea | Adds moisture and stimulates collagen at the same time | Refined skin texture, smaller pores; suitable for dry or dull skin | 6 months |
| Lenisna | HA + PLLA | South Korea | Similar to Juvelook but gives slightly denser, fuller skin | Fuller, firmer, more radiant skin; good for thin skin | 6 months |
| Gouri | PCL | South Korea | Spreads through the skin and stimulates collagen 100% over the face | Firm skin all over the face with an invisible look, no filler lumps | Around 8–12 months |
| Etrebelle | HA + DNA + Peptides | Spain | Creates collagen and nourishes the deeper skin layers | Bright, glowing skin; restores tired and dry skin | About 2–4 months |
| Nabota Sprak (PN) | HA + DNA + Peptides | South Korea | Stimulates cell repair and new skin formation | Younger-looking skin; helps acne marks, wounds and acne scars become shallower | About 4–6 months |
| Plinest | PN | Italy | Restores at DNA level and repairs skin cells deeply | Stronger skin; acne marks fade faster; suitable for sensitive skin | About 4–6 months |
| Medytox PLA | PN | South Korea | Stimulates collagen similar to Sculptra but adjusted for Asian skin | New option gaining popularity; suitable for those who want long-lasting fullness | Around 1 year |
Interested in Biostimulation
A physician will assess and recommend the most suitable plan for each individual.